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白介素15受体α抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Anti-IL15RA
Anti-interleukin 15 receptor subunit alpha Antibody
靶标:

IL15RA


产品别名:

CD215; IL15RA; interleukin 15 receptor subunit alpha; interleukin 15 receptor subunit alpha; interleukin-15 receptor subunit alpha; interleukin 15 receptor, alpha; 白介素15受体α;


背景信息:
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010],
 
 
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