靶标:
IGFALS
产品别名:
ACLSD; ALS; IGFALS; insulin like growth factor binding protein acid labile subunit; insulin like growth factor binding protein acid labile subunit; insulin-like growth factor-binding protein complex acid labile subunit; insulin-like growth factor binding protein complex acid labile chain; 胰岛素样生长因子酸不稳定亚基(IGFALS); 胰岛素样生长因子酸不稳定亚基ALS;
背景信息:
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],