靶标:
HOXB4
产品别名:
HOX-2.6; HOX2; HOX2F; HOXB4; homeobox B4; homeobox B4; homeobox protein Hox-B4; homeo box 2F; homeo box B4; homeobox protein Hox-2.6; homeobox protein Hox-2F;
背景信息:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008],