靶标:
ONECUT1
产品别名:
HNF-6; HNF6; HNF6A; ONECUT1; one cut homeobox 1; one cut homeobox 1; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6, alpha; one cut domain family member 1; 肝细胞核因子6;
背景信息:
This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],