靶标:
HMGB3
产品别名:
HMG-2a; HMG-4; HMG2A; HMG4; HMGB3; high mobility group box 3; high mobility group box 3; high mobility group protein B3; high mobility group protein 2a; high-mobility group (nonhistone chromosomal) protein 4; 高迁移率家族蛋白3; 高迁移率族框蛋白3(HMGB3);
背景信息:
This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],