靶标：
MR1
产品别名：
HLALS； MR1； major histocompatibility complex, class I-related； major histocompatibility complex, class I-related； major histocompatibility complex class I-related gene protein； MHC class I-like antigen MR-1； MHC class I-related protein； MHC class-I related-gene protein； major histocompatibility complex, class I-like sequence； 组织相容性复合物相关蛋白MR1；
背景信息：
Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
