靶标：
HLA-A
产品别名：
HLAA； HLA-A； major histocompatibility complex, class I, A； major histocompatibility complex, class I, A； HLA class I histocompatibility antigen, A alpha chain； HLA class I histocompatibility antigen, A-1 alpha chain； MHC class I antigen HLA-A heavy chain； leukocyte antigen class I-A； Ⅰ类主要组织相容性复合体A(MHCA)； 人类白细胞抗原A； 白细胞抗原A； 组织相容性复合体蛋白1； 组织相容性复合物A2；
背景信息：
HLA-A, namely HLA A, is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is simply the major histocompatibility complex (MHC) specific to humans. HLA-A is one of three major types of human MHC class I cell surface receptors. The others are HLA-B and HLA-C. And it is critical to the cytotoxic t-cell controlled immune response to viruses and other intracellular pathogens. Because each HLA-A gene has a high affinity for slightly different peptides, certain HLA-As are associated with increased risk, more rapid progression, and/or increased severity of many diseases. For similar reasons, HLA-A matching is essential to successful tissue transplants.
