靶标：
CFHR1
产品别名：
CFHL； CFHL1； CFHL1P； CFHR1P； FHR-1； FHR1； H36； H36-1； H36-2； HFL1； HFL2； CFHR1； complement factor H related 1； complement factor H related 1； complement factor H-related protein 1； H factor (complement)-like 1； H factor (complement)-like 2； H-factor-like 1； complement factor H-related 1 pseudogene； h factor-like protein 1； 补体因子H相关蛋白1； 补体因子H相关蛋白1(CFHR1)；
背景信息：
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009],
