靶标：
SERPIND1
产品别名：
D22S673； HC2； HCF2； HCII； HLS2； LS2； THPH10； SERPIND1； serpin family D member 1； serpin family D member 1； heparin cofactor 2； leuserpin 2； protease inhibitor leuserpin-2； serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1； serpin D1； serpin peptidase inhibitor, clade D (heparin cofactor), member 1； 肝素辅因子Ⅱ(HCII)；
背景信息：
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015],
