靶标:
GUCY1B1
产品别名:
GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B3; GUCY1B1; guanylate cyclase 1 soluble subunit beta 1; guanylate cyclase 1 soluble subunit beta 1; guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; guanylate cyclase 1, soluble, beta 3; guanylate cyclase soluble subunit beta-3; soluble guanylate cyclase small subunit; 鸟苷酸环化酶1β3(GUCY1b3); 鸟苷酸环化酶β1;
背景信息:
This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],