靶标：
GRIK2
产品别名：
EAA4； GLR6； GLUK6； GLUR6； GluK2； MRT6； NEDLAS； GRIK2； glutamate ionotropic receptor kainate type subunit 2； glutamate ionotropic receptor kainate type subunit 2； glutamate receptor ionotropic, kainate 2； GluK2(alt_5'UTR)； bA487F5.1； excitatory amino acid receptor 4； gluR-6； glutamate receptor 6； glutamate receptor form A； glutamate receptor form B； glutamate receptor form C； glutamate receptor form D； glutamate receptor form E； putative NMDtranscript(cassette_171nt)； 红藻氨酸离子能谷氨酸受体2(GRIK2)； 谷氨酸受体红藻氨酸离子2/3； 谷氨酸受体红藻氨酸离子2/谷氨酸受体6；
背景信息：
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],
