靶标：
RAPGEF1
产品别名：
C3G； GRF2； RAPGEF1； Rap guanine nucleotide exchange factor 1； Rap guanine nucleotide exchange factor 1； rap guanine nucleotide exchange factor 1； CRK SH3-binding GNRP； Rap guanine nucleotide exchange factor (GEF) 1； guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)； G蛋白偶联受体释放因子2； Rap鸟嘌呤核苷酸交换因子1(RAPGEF1)；
背景信息：
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
