靶标:
GPR3
产品别名:
ACCA; GPR3; G protein-coupled receptor 3; G protein-coupled receptor 3; G-protein coupled receptor 3; ACCA orphan receptor; adenylate cyclase constitutive activator; G蛋白偶联受体3;
背景信息:
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012],