靶标:
GDI2
产品别名:
HEL-S-46e; RABGDIB; GDI2; GDP dissociation inhibitor 2; GDP dissociation inhibitor 2; rab GDP dissociation inhibitor beta; GDI-2; epididymis secretory sperm binding protein Li 46e; guanosine diphosphate dissociation inhibitor 2; rab GDI beta; rab GDP-dissociation inhibitor, beta;
背景信息:
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],