靶标:
GDF10
产品别名:
BIP; BMP-3b; BMP3B; GDF10; growth differentiation factor 10; growth differentiation factor 10; growth/differentiation factor 10; bone morphogenetic protein 3B; bone-inducing protein; 生长分化因子10; 生长分化因子10(GDF10);
背景信息:
growth differentiation factor 10(GDF10) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016],