靶标：
GCNT2
产品别名：
CCAT； CTRCT13； GCNT2C； GCNT5； IGNT； II； NACGT1； NAGCT1； ULG3； bA360O19.2； bA421M1.1； GCNT2； glucosaminyl (N-acetyl) transferase 2 (I blood group)； glucosaminyl (N-acetyl) transferase 2 (I blood group)； N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase； I beta-1,6-N-acetylglucosaminyltransferase； Ii blood group； beta-1,6-N-acetylglucosaminyltransferase 2； glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)； β1-6 N-乙酰氨基葡萄糖转移酶2； β1-6 N-乙酰氨基葡萄糖转移酶6；
背景信息：
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
