靶标：
GBE1
产品别名：
APBD； GBE； GSD4； GBE1； 1,4-alpha-glucan branching enzyme 1； 1,4-alpha-glucan branching enzyme 1； 1,4-alpha-glucan-branching enzyme； amylo-(1,4 to 1,6) transglucosidase； amylo-(1,4 to 1,6) transglycosylase； brancher enzyme； glucan (1,4-alpha-), branching enzyme 1； glycogen branching enzyme； 分支酶GBE1；
背景信息：
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).
