靶标：
GALNS
产品别名：
GALNAC6S； GAS； GalN6S； MPS4A； GALNS； galactosamine (N-acetyl)-6-sulfatase； galactosamine (N-acetyl)-6-sulfatase； N-acetylgalactosamine-6-sulfatase； N-acetylgalactosamine-6-sulfate sulfatase； chondroitinase； chondroitinsulfatase； galNAc6S sulfatase； galactosamine (N-acetyl)-6-sulfate sulfatase； galactose-6-sulfate sulfatase； N-乙酰硫酸酯酶(GALNS)； 硫酸软骨素裂解酶；
背景信息：
N-acetylgalactosamine-6-sulfatase is an enzyme that, in humans, is encoded by the GALNS gene. This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.
