靶标:
GABRA5
产品别名:
DEE79; EIEE79; GABRA5; gamma-aminobutyric acid type A receptor subunit alpha5; gamma-aminobutyric acid type A receptor subunit alpha5; gamma-aminobutyric acid receptor subunit alpha-5; GABA(A) receptor subunit alpha-5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid type A receptor alpha5 subunit; γ1氨基丁酸受体α5/GABRα5;
背景信息:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008],