靶标:
FOXE1
产品别名:
FKHL15; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; TTF2; FOXE1; forkhead box E1; forkhead box E1; forkhead box protein E1; HNF-3/fork head-like protein 5; forkhead box protein E2; forkhead, drosophila, homolog-like 15; forkhead-related protein FKHL15; thyroid transcription factor 2; 甲状腺转录因子-2;
背景信息:
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I. [provided by RefSeq, Jul 2008],