靶标:
FKBP2
产品别名:
FKBP-13; FKBP13; PPIase; FKBP2; FKBP prolyl isomerase 2; FKBP prolyl isomerase 2; peptidyl-prolyl cis-trans isomerase FKBP2; 13 kDa FK506-binding protein; 13 kDa FKBP; FK506 binding protein 2, 13kDa; FK506-binding protein 2; PPIase FKBP2; epididymis secretory sperm binding protein; immunophilin FKBP13; proline isomerase; rapamycin-binding protein; rotamase; FK506结合蛋白2(FKBP2); FKBP2蛋白;
背景信息:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008],