靶标:
VEGFD
产品别名:
FIGF; VEGF-D; VEGFD; vascular endothelial growth factor D; vascular endothelial growth factor D; vascular endothelial growth factor D; c-fos induced growth factor (vascular endothelial growth factor D); 血管内皮生长因子D(VEGFD); 血管内皮生长因子D型;
背景信息:
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011],