靶标:
FGF3
产品别名:
HBGF-3; INT2; FGF3; fibroblast growth factor 3; fibroblast growth factor 3; fibroblast growth factor 3; FGF-3; INT-2 proto-oncogene protein; V-INT2 murine mammary tumor virus integration site oncogene homolog; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog); heparin-binding growth factor 3; murine mammary tumor virus integration site 2, mouse; oncogene INT2; proto-oncogene Int-2; 成纤维细胞生长因子3(FGF3); 纤维母细胞生长因子3;
背景信息:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008],