靶标：
SERPINB1
产品别名：
EI； ELANH2； HEL-S-27； HEL57； LEI； M/NEI； MNEI； PI-2； PI2； SERPINB1； serpin family B member 1； serpin family B member 1； leukocyte elastase inhibitor； epididymis luminal protein 57； epididymis secretory protein Li 27； peptidase inhibitor 2； protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived； serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1； serpin peptidase inhibitor, clade B (ovalbumin), member 1； 丝氨酸蛋白酶抑制剂B1； 白细胞弹性蛋白酶抑制因子(LEI)；
背景信息：
Leukocyte elastase inhibitor (LEI) also known as serpin B1 is a protein that in humans is encoded by the SERPINB1 gene. The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
