靶标:
EIF2B1
产品别名:
EIF2B; EIF2BA; EIF2Balpha; EIF2B1; eukaryotic translation initiation factor 2B subunit alpha; eukaryotic translation initiation factor 2B subunit alpha; translation initiation factor eIF-2B subunit alpha; eIF-2B GDP-GTP exchange factor subunit alpha; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; eIF2B1蛋白;
背景信息:
Translation initiation factor eIF-2B subunit alpha is a protein that in humans is encoded by the EIF2B1 gene. This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.