靶标：
DSC2
产品别名：
ARVD11； CDHF2； DG2； DGII/III； DSC3； DSC2； desmocollin 2； desmocollin 2； desmocollin-2； cadherin family member 2； desmosomal glycoprotein II/III； 桥粒糖蛋白2/桥粒糖蛋白3； 桥粒芯胶粘蛋白2(DSC2)；
背景信息：
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],
