靶标：
CYP51A1
产品别名：
CP51； CYP51； CYPL1； LDM； P450-14DM； P450L1； CYP51A1； cytochrome P450 family 51 subfamily A member 1； cytochrome P450 family 51 subfamily A member 1； lanosterol 14-alpha demethylase； CYPLI； cytochrome P450 51A1； cytochrome P450, 51 (lanosterol 14-alpha-demethylase)； cytochrome P450, family 51, subfamily A, polypeptide 1； cytochrome P450-14DM； cytochrome P45014DM； cytochrome P450LI； sterol 14-alpha demethylase； 羊毛甾醇14α-去甲基化酶蛋白；
背景信息：
cytochrome P450 family 51 subfamily A member 1(CYP51A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
