靶标:
CYP24A1
产品别名:
CP24; CYP24; HCAI; HCINF1; P450-CC24; CYP24A1; cytochrome P450 family 24 subfamily A member 1; cytochrome P450 family 24 subfamily A member 1; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 1,25-@dihydroxyvitamin D3 24-hydroxylase; 24-OHase; cytochrome P450 24A1; cytochrome P450, family 24, subfamily A, polypeptide 1; cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase); cytochrome P450-CC24; exo-mitochondrial protein; lncBCAS1-4_1; vitamin D 24-hydroxylase; vitamin D(3) 24-hydroxylase; 细胞色素P450 24A1; 细胞色素P450家族成员24A1(CYP24A1);
背景信息:
cytochrome P450 family 24 subfamily A member 1(CYP24A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],