靶标:
CYP3A7
产品别名:
CP37; CYPIIIA7; P-450(HFL33); P-450111A7; P450-HFLA; P450HLp2; CYP3A7; cytochrome P450 family 3 subfamily A member 7; cytochrome P450 family 3 subfamily A member 7; cytochrome P450 3A7; aryl hydrocarbon hydroxylase; cytochrome P450, family 3, subfamily A, polypeptide 7; cytochrome P450, subfamily IIIA, polypeptide 7; cytochrome P450-HFLA; flavoprotein-linked monooxygenase; microsomal monooxygenase; xenobiotic monooxygenase; 细胞色素P450 A7; 细胞色素P450家族成员3A7(CYP3A7);
背景信息:
This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015],