靶标:
CRHBP
产品别名:
CRF-BP; CRFBP; CRHBP; corticotropin releasing hormone binding protein; corticotropin releasing hormone binding protein; corticotropin-releasing factor-binding protein; CRF-binding protein; CRH-BP; 促肾上腺皮质激素释放激素结合蛋白; 促肾上腺皮质素释放激素结合蛋白(CRHBP);
背景信息:
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008],