靶标:
CPN1
产品别名:
CPN; SCPN; CPN1; carboxypeptidase N subunit 1; carboxypeptidase N subunit 1; carboxypeptidase N catalytic chain; anaphylatoxin inactivator; arginine carboxypeptidase; carboxypeptidase K; carboxypeptidase N catalytic subunit; carboxypeptidase N polypeptide 1 50 kD; carboxypeptidase N small subunit; carboxypeptidase N, polypeptide 1; kininase I; kininase-1; lysine carboxypeptidase; plasma carboxypeptidase B; serum carboxypeptidase N; 激肽酶1; 羧肽酶N1(CPN1);
背景信息:
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008],