靶标:
CPE
产品别名:
BDVS; CPH; IDDHH; CPE; carboxypeptidase E; carboxypeptidase E; carboxypeptidase E; carbocypeptidase E; carboxypeptidase H; cobalt-stimulated chromaffin granule carboxypeptidase; enkephalin convertase; epididymis secretory sperm binding protein; insulin granule-associated carboxypeptidase; prohormone-processing carboxypeptidase; 羧肽酶E(CPE); 胰羧肽酶E;
背景信息:
carboxypeptidase E(CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015],