靶标：
CNGA4
产品别名：
CNCA2； CNG-4； CNG4； CNG5； CNGB2； OCNC2； OCNCBETA； OCNCb； CNGA4； cyclic nucleotide gated channel subunit alpha 4； cyclic nucleotide gated channel subunit alpha 4； cyclic nucleotide-gated cation channel alpha-4； CNG channel alpha-4； cyclic nucleotide gated channel alpha 4； cyclic nucleotide gated channel beta 2；
背景信息：
Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
