靶标：
ACKR2
产品别名：
CCBP2； CCR10； CCR9； CMKBR9； D6； hD6； ACKR2； atypical chemokine receptor 2； atypical chemokine receptor 2； atypical chemokine receptor 2； C-C chemokine receptor D6； CC-chemokine-binding receptor JAB61； chemokine (C-C motif) receptor 9； chemokine (C-C) receptor 9； chemokine receptor CCR-10； chemokine receptor CCR-9； chemokine receptor D6； chemokine-binding protein 2； chemokine-binding protein D6； 趋化因子受体D6； 趋化因子结合蛋白2；
背景信息：
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008],
