靶标：
CCR8
产品别名：
CC-CKR-8； CCR-8； CDw198； CKRL1； CMKBR8； CMKBRL2； CY6； GPRCY6； TER1； CCR8； C-C motif chemokine receptor 8； C-C motif chemokine receptor 8； C-C chemokine receptor type 8； CC chemokine receptor 8； CC chemokine receptor CHEMR1； CC-chemokine receptor chemr1； chemokine (C-C motif) receptor 8； chemokine (C-C) receptor 8； chemokine (C-C) receptor-like 2； chemokine receptor-like 1； 细胞表面趋化因子受体8； 趋化因子C-C-基元受体8(CCR8)；
背景信息：
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008],
