靶标：
TPP1
产品别名：
CLN2； GIG1； LPIC； SCAR7； TPP-1； TPP1； tripeptidyl peptidase 1； tripeptidyl peptidase 1； tripeptidyl-peptidase 1； cell growth-inhibiting gene 1 protein； growth-inhibiting protein 1； lysosomal pepstatin insensitive protease； lysosomal pepstatin-insensitive carboxypeptidase； tripeptidyl aminopeptidase； tripeptidyl peptidase I； 三肽基肽酶Ⅰ(TPP1)； 细胞生长抑制基因1蛋白；
背景信息：
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008],
