靶标:
CEL
产品别名:
BAL; BSDL; BSSL; CELL; CEase; FAP; FAPP; LIPA; MODY8; CEL; carboxyl ester lipase; carboxyl ester lipase; bile salt-activated lipase; bucelipase; carboxyl ester hydrolase; carboxyl ester lipase (bile salt-stimulated lipase); cholesterol esterase; fetoacinar pancreatic protein; lysophospholipase, pancreatic; sterol esterase; 胆盐依赖性脂肪酶(BSDL); 胆盐激活脂肪酶;
背景信息:
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008],