靶标：
CAPN3
产品别名：
CANP3； CANPL3； LGMD2； LGMD2A； LGMDD4； LGMDR1； nCL-1； p94； CAPN3； calpain 3； calpain 3； calpain-3； calpain p94, large [catalytic] subunit； calpain, large polypeptide L3； muscle-specific calcium-activated neutral protease 3 large subunit； new calpain 1； 钙蛋白酶3(CAPN3)；
背景信息：
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008],
