靶标:
CACNA2D1
产品别名:
CACNA2; CACNL2A; CCHL2A; LINC01112; lncRNA-N3; CACNA2D1; calcium voltage-gated channel auxiliary subunit alpha2delta 1; calcium voltage-gated channel auxiliary subunit alpha2delta 1; voltage-dependent calcium channel subunit alpha-2/delta-1; alpha2delta-1; calcium channel, L type, alpha 2 polypeptide; calcium channel, voltage-dependent, alpha 2/delta subunit 1; dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit; voltage-gated calcium channel subunit alpha-2/delta-1; 钙通道L型α2多肽;
背景信息:
calcium voltage-gated channel auxiliary subunit alpha2delta 1(CACNA2D1) Homo sapiens The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014],