靶标：
BUB1
产品别名：
BUB1A； BUB1L； hBUB1； BUB1； BUB1 mitotic checkpoint serine/threonine kinase； BUB1 mitotic checkpoint serine/threonine kinase； mitotic checkpoint serine/threonine-protein kinase BUB1； BUB1 budding uninhibited by benzimidazoles 1 homolog； budding uninhibited by benzimidazoles 1 homolog； mitotic spindle checkpoint kinase； putative serine/threonine-protein kinase； 纺锤体检查点蛋白；
背景信息：
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
