靶标:
BTG1
产品别名:
APRO2; BTG1; BTG anti-proliferation factor 1; BTG anti-proliferation factor 1; protein BTG1; B-cell translocation gene 1 protein; B-cell translocation gene 1, anti-proliferative; B细胞迁移基因1;
背景信息:
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008],