靶标：
BMP8B
产品别名：
BMP8； OP2； BMP8B； bone morphogenetic protein 8b； bone morphogenetic protein 8b； bone morphogenetic protein 8B； bone morphogenetic protein 8 (osteogenic protein 2)； osteogenic protein 2； 骨形态发生蛋白8； 骨形态发生蛋白8b； 骨形成蛋白8B(BMP8B)；
背景信息：
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016],
