靶标:
BLMH
产品别名:
BH; BMH; BLMH; bleomycin hydrolase; bleomycin hydrolase; bleomycin hydrolase; BLM hydrolase; 博来霉素水解酶(BLMH); 博莱霉素水解酶;
背景信息:
Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008],