靶标：
ATP7B
产品别名：
PWD； WC1； WD； WND； ATP7B； ATPase copper transporting beta； ATPase copper transporting beta； copper-transporting ATPase 2； ATPase, Cu(2+)- transporting, beta polypeptide； ATPase, Cu++ transporting, beta polypeptide； Wilson disease-associated protein； copper pump 2； copper-transporting protein ATP7B； 铜离子转运ATP酶β肽(ATP7b)； 铜转运蛋白质β链；
背景信息：
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008],
