靶标:
ATOX1
产品别名:
ATX1; HAH1; ATOX1; antioxidant 1 copper chaperone; antioxidant 1 copper chaperone; copper transport protein ATOX1; ATX1 antioxidant protein 1 homolog; metal transport protein ATX1;
背景信息:
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.