靶标:
AGTR2
产品别名:
AT2; ATGR2; MRX88; AGTR2; angiotensin II receptor type 2; angiotensin II receptor type 2; type-2 angiotensin II receptor; angiotensin II type-2 receptor; 血管紧张素Ⅱ受体2; 血管紧张素Ⅱ受体2(AGTR2);
背景信息:
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010],