靶标:
TLE5
产品别名:
AES; AES-1; AES-2; ESP1; GRG; GRG5; Grg-5; TLE5; TLE family member 5, transcriptional modulator; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; gp130-associated protein GAM; groucho-related protein 5; gp130结合蛋白GAM;
背景信息:
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],