靶标:
ADAM8
产品别名:
CD156; CD156a; MS2; ADAM8; ADAM metallopeptidase domain 8; ADAM metallopeptidase domain 8; disintegrin and metalloproteinase domain-containing protein 8; a disintegrin and metalloproteinase domain 8; cell surface antigen MS2; human leukocyte differentiation antigen; 去整合素样金属蛋白酶8; 解整合素金属蛋白酶8(ADAM8);
背景信息:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009],