脑钠通道蛋白1抗体

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脑钠通道蛋白1抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Anti-ASIC2
Anti-acid sensing ion channel subunit 2 Antibody

靶标：

ASIC2

产品别名：

ACCN； ACCN1； ASIC2a； BNC1； BNaC1； MDEG； hBNaC1； ASIC2； acid sensing ion channel subunit 2； acid sensing ion channel subunit 2； acid-sensing ion channel 2； acid sensing (proton gated) ion channel 2； amiloride-sensitive cation channel 1, neuronal； brain sodium channel 1； mammalian degenerin homolog； neuronal amiloride-sensitive cation channel 1；脑钠通道蛋白1；

背景信息：

Amiloride-sensitive cation channel 1, neuronal, also known as ASIC2, is a protein that in humans is encoded by the ACCN1 gene. This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.