靶标：
ABCA2
产品别名：
ABC2； IDPOGSA； ABCA2； ATP binding cassette subfamily A member 2； ATP binding cassette subfamily A member 2； ATP-binding cassette sub-family A member 2； ATP-binding cassette 2； ATP-binding cassette transporter 2； ATP-binding cassette, sub-family A (ABC1), member 2； ATP-binding cassette, sub-family A, member 2； ATP结合盒转运蛋白A2(ABCA2)； 三磷酸腺苷结合盒转运蛋白2；
背景信息：
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.
